Our Services

Our Services

Fast, reliable and inexpensive pre-clinical claim validation for cosmeceutical products before you start spending heavily on clinical studies. Located among the orchards of Santa Paula (Ventura county, Southern CA), Sunny BioDiscovery, Inc. has been in the Research & Development business for over 20 years and our science has been honored by several NIH grants, including from the National Institute on Aging and National Cancer Institute.

We have worked with many publicly and privately held companies, enabling them to validate the bioactive potential of their ingredients. You can entrust your materials to us for a fast, precise and professional service. At Sunny BioDiscovery, your compounds will be custom-tested under the supervision of an experienced PhD or MD scientist, who will then prepare a written report and will be available for discussing the results over the phone. We guarantee the quality and the confidentiality of our services.

We specialize in custom tests and method development for:

Scientific validation of bioactivity claims

Testing of active materials for new bioactivities

Development of new cosmetic claim concepts backed by scientific publications (see "Science" page)

Highlights

Intradermal, transdermal and trans stratum corneum permeation (Strat M and PAMPA models)

Over 30 standard tests for skin-relevant bioactivities (eg. collagen and hyaluronic acid stimulation, antioxidant activity, inhibition of MMPs, inflammation, Advenced Glycation Endproducts…)

Tests on Cell Cultures, Skin Substitutes and human skin biopsies [inhibition of senescence, mitophagy, whitening, irritation, skin penetration, proteins of skin barrier and extracellular matrix (ECM)…]

Transcriptome Analysis: PCR arrays, RNA-seq, DNA microarrays (Anti-aging, anti-inflammation, skin structure, wound healing, and more)

Phototoxicity, cell & skin viability, human dermal fibroblast & keratinocyte proliferation assays, reporter assays for transcriptional regulation by retinoic acid nuclear receptors, PPARs and other transcription factors.

HPLC, LC-MS, Fluorometry, TLC, Spectrophotometry, Chemoluminescence, Cell Imaging, Skin Oxygenation