Publications in Peer-reviewed Journals

1) YR Wang, H Zhao, XS Sheng, PE Gambino, B Costello, and K Bojanowski: Protective effect of Fructus Lycii Polysaccharides against time- and hyperthermia-induced damage
in cultured seminiferous epithelium
J. Ethnopharmacol. 82:169-175, 2002.

2) E Atlas, K Bojanowski, I Mehmi, R Lupu: A deletion mutant of heregulin increases the sensitivity of breast cancer cells to chemotherapy without promoting tumorigenicity.
Oncogene. 22:3441-3451, 2003.

3) H Zhao, A Alexeev, E Chang, G Greenburg and K Bojanowski: Lycium barbarum glycoconjugates: effect on whole skin and cultured dermal fibroblasts. Phytomedicine, 12:
132-138, 2005.

4) H Zhao, F Aria, R Mortezaei, YR Wang, XS Sheng and K Bojanowski:
SBD.4 Stimulates Regenerative Processes In Vitro and Wound Healing in Genetically Diabetic Mice and in Human Skin/SCID Mouse Chimera. Wound Repair & Regeneration,
14:593-601, 2006.

5) H Zhao, A Alexeev, V Sharma, LD Guzman, K Bojanowski: Effect of SBD.4A - a defined multicomponent preparation of Angelica sinensis - in periodontal regeneration models.
Phytother Res. 22:923-928, 2008.

6) J Deneau, T Ahmed, R Blotsky, K Bojanowski: Anti-Diabetic Activity of a Mineraloid Isolate, In Vitro and in Genetically Diabetic Mice. Int. J. Vitam. Nutr. Res. (Switzerland). 81:1-
8, 2011.

7) K Gobis, H Foks, K Bojanowski, E Augustynowicz-Kopeć, A Napiórkowska: Synthesis of novel 3-cyclohexylpropanoic acid-derived nitrogen heterocyclic compounds and their
evaluation for tuberculostatic activity.
Bioorg Med Chem. 20:37-144, 2012.

8) H Zhao, J Deneau, G O L Che, S Li, F. Vagnini, P Azadi, R Sonon, R Ramjit, S M Y Lee and K Bojanowski: Angelica sinensis Isolate SBD.4: Composition, Gene Expression
Profiling, Mechanism of Action, and Effect on Wounds in Rats and Humans.
Eur. J. Dermatol. 22:58-67, 2012.

9) K Gobis, H Foks, J Sławiński, A Sikorski, D Trzybiński, E Augustynowicz-Kopeć, A Napiórkowska, K Bojanowski: Synthesis and Biological Activity of Novel Heterocyclic Sulfonyl-
carboximidamides
Monatshefte für Chemie – Chemical Monthly 144:647-658, 2013

10) K Bojanowski: Hypodermal delivery of cosmetic actives for improved facial skin morphology and functionality. Int J Cosmet Sci. doi: 10.1111/ics.12077, 2013.

11) RK Chaudhuri, K Bojanowski: Bakuchiol: a retinol-like functional compound revealed by gene expression profiling and clinically proven to have anti-aging effects. Int J
Cosmet Sci
. 221-230, 2014.

12) H Zhao, K Bojanowski: Hypodermis: the last frontier for facial cosmetics. H&PC Today 9:38-42, 2014.

13) K Gobis, H Foks, K Suchan, E Augustynowicz-Kopeć, A Napiórkowska, K Bojanowski: Novel 2-(2-phenalkyl)-1H-benzo[d]imidazoles as antitubercular agents. Synthesis,
biological evaluation and structure-activity relationship.
Bioorg Med Chem. pii: S0968-0896(15)00173-X, 2015.

14) H Zhao, K Bojanowski: Dermatologic Uses and Effects of Lycium barbarum. In “Lycium barbarum and human health” Ed. RCC Chang and K Fai, (Springer), 79-8, 2015.

15) K Bojanowski, R Bojanowski: Two methods of oral delivery of resveratrol: a case study. Journal of Aging Research and Clinical Practice (JARCP), 4 (3), 185-189, 2015.

16) S Ma, K Gobis, WR Swindell, R Chaudhuri, R Bojanowski, K Bojanowski: Synthesis and activity of the salicylic acid ester of bakuchiol in psoriasis-surrogate keratinocytes
and skin substitutes.
Clin Exp Dermatol. 42:251-260, 2017.

17) RK Chaudhuri, K Bojanowski: Improvement of Hydration and Epidermal Barrier Function in Human Skin by a Novel Compound Isosorbide Dicaprylate. Int J Cosmet Sci. 39:
518-526, 2017

18) WR Swindell, K Bojanowski, MS Kindy, RMW Chau, D Ko: GM604 regulates developmental neurogenesis pathways and the expression of genes associated with
amyotrophic lateral sclerosis.
Translational Neurodegeneration 7:30, 2018

19) M Kindy, WR Swindell, K Bojanowski, P Lupinacci, R Bowser, R Nir, M Westlin, J Evans, T Shum, R Chau, D Ko: GM6, an Endogenous Multiple-Target Regulator that
Provides a Novel Therapeutic Strategy for Treatment of ALS and Other Neurodegenerative Diseases.
Neurotherapeutics 15 (3), 820-821, 2018

20) WR Swindell, K Bojanowski, R Chaudhuri: A Zingerone Analog, Acetyl Zingerone, bolsters matrisome synthesis, inhibits matrix metallopeptidases, and represses IL-17A
target gene expression.
J Invest Dermatol. 140 (3):602-61, 2020

21) M Krause, H Foks, D Ziembicka, E Augustynowicz-Kopeć, A Głogowska, I Korona-Głowniak, K Bojanowski, D Siluk, K Gobis K: 4-Substituted picolinohydrazonamides as a
new class of potential antitubercular agents.
Eur J Med Chem. 15;190:112106, 2020

22) Bojanowski K, Corona P, Ma S, Zhao H: A noninvasive myorelaxant approach resulting in gummy smile improvement-A pilot study. J Cosmet Dermatol. Jun 15., 2020

23) K Bojanowski, S Ma, R Applebaum, H Zhao: Transbuccal platform for delivery of lipogenic actives to facial skin: Because fat matters. J Tissue Eng Regen Med. Aug;14(8):
1169-1174, 2020

24) WR Swindell, K Bojanowski, R Chaudhuri: A novel fumarate, isosorbide di-(methyl fumarate) (IDMF), replicates astrocyte transcriptome responses to dimethyl fumarate
(DMF) but specifically down-regulates genes linked to a reactive phenotype.
Biochem Biophys Res Commun. 2020 3:S0006-291X(20)31676-4, 2020

25) WR Swindell, K Bojanowski, R Chaudhuri: A standardized Terminalia chebula fruit extract alters the expression of genes associated with skin architecture and barrier
formation.
Eur. J. Dermatol. 30(5):469-49, 2020

26) K Bojanowski, WR Swindell, S Cantor, R Chaudhuri: Isosorbide Di-(Linoleate/Oleate) Stimulates Prodifferentiation Gene Expression to Restore the Epidermal Barrier and
Improve Skin Hydration.
J Invest Dermatol. In press, 2021


Other Publications

G Gillis, K Bojanowski, G Majewski, R Bohm: UpRegulex - Sericin peptides from silk protein. Cosmetic Science Technology, 30-33, 2009

R Chaudhuri, K Bojanowski, F. Marchio: Le rétinol et les composés rétinol-like en soins cutanés. Expressions Cosmetiques, 227-233, 2010

BA Green, BL Edison, K Bojanowski, RL Weinkauf: Antiaging bionic and polyhydroxy acids reduce nonenzymatic protein glycation and skin sallowness. Journal of the American
Academy of Dermatology 70 (5), AB22-AB22, 2014

WR Swindell, K Bojanowski, M Kindy, T Shum, R Chau, D Ko: GM604 represses tau and down-regulates expression of mitochondrial genes associated with Alzheimer’s disease.
F1000Research 5, 2016

WR Swindell, K Bojanowski, M Kindy, T Shum, R Chou, D Ko: GM604 for Parkinson's Disease treatment: pre-clinical findings and results from a pilot placebo-controlled trial
F1000Research 6, 2017

Krzysztof Bojanowski, Tai An Pan, Hui Zhao, Rong Guo:  Goji (Lycium barbarum) Glycoconjugates: Application in Functional Foods. Chapter 6. Phytochemicals in Goji Berries
Applications in Functional Foods, Edited by Xingqian Ye, Yueming Jiang, CRC Press, 06 2020



Presentations & Invited Lectures

K Bojanowski and H Zhao: Importance of glycosylation for the activity of a new anticancer angiogenesis inhibitor SBD.1. Poster at Gordon Conference on
Carbohydrates, Tilton, 2001

K Bojanowski: Skin Care through the Protection of Dermal Microcirculation. Invited lecture at Personal Care Ingredients Technology Expo. New York, 2003

K Bojanowski: Product development for niche markets - in vitro validation approach. Invited lecture at Personal Care Ingredients  Technology Expo. New York, 2005

H Zhao, F Aria, V Sharma, A Alexeev, R Mortezaei and K Bojanowski: SBD.4 - A Modular Technology for the Development of Products for Skin,
Wounds and Periodontal Diseases. UCSF 2006 Life Science Innovation Competition Finals. San Francisco, 2006 (Presentation awarded People's Choice Award)

K Bojanowski: Hybrid Compounds: A Growing Trend in Cosmeceuticals. Strategic Research Institute's (SRI) 4th Annual Cosmeceuticals Conference. New York, 2007  

K Bojanowski: Non-clinical Testing of Cosmetic Actives for Special Needs and Aging Skin. ACCELERATING THE FUTURE. Ingredient & Technology Conference New
York, 2008.

K Bojanowski, J Deneau, OL Che, SMY Lee, F Vagnini and R Ramjit: SBD.4-Based Wound Dressings: the “Green” Revolution in Chronic Ulcer Management. Symposium
on Advanced Wound Care, Anaheim, 2010.

K Gobis, H Foks, E Augustynowicz-Kopeć, and K Bojanowski. Synthesis and tuberculostatic activity of novel 2-(2-cyclohexylethyl)-lH-benzo[ d]imidazoles.
Multidysciplinary Conference on Drug Research, Ossa, 2012.

R Chaudhuri, K Bojanowski. Cyclobutane Pyrimidine Dimers, NADPH Oxidase and Peroxynitrite: How Are They All Interlinked? 29th IFSCC Congress, Orlando, 2016.

WR Swindell, K Bojanowski, M Kindy, T Shum, R Chau, D Ko. GM604 for Parkinson's Disease treatment: Pre-clinical findings and results from a pilot placebo-controlled
trial. F1000Research 6:28 (doi: 10.7490/f1000research.1113600. 1), 2017.

Ratan K Chaudhuri, Krys Bojanowski, Parvesh Singh. Delayed DNA Damage - How Significant this Pathway is for Skin Damage? NYSCC Annnual Meeting presentation,
2017.

Mark Kindy, William R. Swindell, Krzysztof Bojanowski, Paul Lupinacci, Robert Bowser, Raphael Nir, Tony Shum, Raymond Chau, Dorothy Ko. GM604 –An Endogenous
Multiple-Target Regulator that Provides a Novel Therapeutic Strategy for Treatment of ALS and Other Neurodegenerative Diseases. 28th National Symposium on
ALS/MND, Boston, 2017.

Krys Bojanowski. Improving Smile Line and Facial Regeneration through Bioadhesive Intraoral Films: The First Dental Office - Friendly Skin Care Cosmetic. 73rd Annual
Meeting of the Society of Cosmetic Chemists in New York, Dec. 2019.



Patents

For the intellectual property portfolio of Sunny BioDiscovery (six issued and two pending patents) please contact Dr. Krys Bojanowski at
kbojanowski@sunnybiodiscovery.com
Sunny BioDiscovery, Inc.
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